Microdialysis Sampling from Wound Fluids Enables Quantitative Assessment of Cytokines, Proteins, and Metabolites Reveals Bone Defect-Specific Molecular Profiles

• Yvonne Förster ,

  Contributed equally to this work with: Yvonne Förster, Johannes R. Schmidt

  * E-mail: yvonne.foerster@uniklinikum-dresden.de

  Affiliation University Center of Orthopedics and Trauma Surgery and Center for Translational Bone, Joint and Soft Tissue Research, University Hospital “Carl Gustav Carus”, TU Dresden, Dresden, Germany

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• Johannes R. Schmidt ,

  Contributed equally to this work with: Yvonne Förster, Johannes R. Schmidt

  Affiliation Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany

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• Dirk K. Wissenbach,

  Affiliation Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany

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• Susanne E. M. Pfeiffer,

  Affiliation Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany

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• Sven Baumann,

  Affiliations Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany, Institute of Pharmacy, Faculty of Biosciences, Pharmacy and Psychology, University of Leipzig, Leipzig, Germany

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• Lorenz C. Hofbauer,

  Affiliation Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, University Hospital “Carl Gustav Carus”, TU Dresden, Dresden, Germany

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• Martin von Bergen,

  Affiliations Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany, Institute of Biochemistry, Faculty of Biosciences, Pharmacy and Psychology, University of Leipzig, Leipzig, Germany, Centre for Microbial Communities, University of Aalborg, Aalborg East, Denmark

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• Stefan Kalkhof,

  Affiliations Department of Molecular Systems Biology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany, Department of Bioanalytics, University of Applied Sciences and Arts of Coburg, Coburg, Germany

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• Stefan Rammelt

  Affiliations University Center of Orthopedics and Trauma Surgery and Center for Translational Bone, Joint and Soft Tissue Research, University Hospital “Carl Gustav Carus”, TU Dresden, Dresden, Germany, Center for Regenerative Therapies Dresden (CRTD), Dresden, Germany

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