CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling

Open Access

Peer-reviewed

Research Article

José A. Rodríguez-Nieves,

Affiliation Center for Personalized Cancer Therapy and Department of Biology, University of Massachusetts, Boston, Massachusetts
⨯
Susan C. Patalano,

Affiliation Center for Personalized Cancer Therapy and Department of Biology, University of Massachusetts, Boston, Massachusetts
⨯
Diego Almanza,

Affiliation Center for Personalized Cancer Therapy and Department of Biology, University of Massachusetts, Boston, Massachusetts
⨯
Mehrnaz Gharaee-Kermani,

Affiliation Center for Personalized Cancer Therapy and Department of Biology, University of Massachusetts, Boston, Massachusetts
⨯
Jill A. Macoska

* E-mail: Jill.Macoska@umb.edu

Affiliation Center for Personalized Cancer Therapy and Department of Biology, University of Massachusetts, Boston, Massachusetts
⨯

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Fibroblasts
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Prostate gland
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EGFR signaling
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SMAD signaling
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Collagens
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ERK signaling cascade
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Transactivation
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Small interfering RNA
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