Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3

Tsepo Lebiletsa Tsekoa; Therese Lotter-Stark; Sindisiwe Buthelezi; Ereck Chakauya; Stoyan H. Stoychev; Claude Sabeta; Wonderful Shumba; Baby Phahladira; Steve Hume; Josh Morton; Charles E. Rupprecht; Herta Steinkellner; Michael Pauly; Larry Zeitlin; Kevin Whaley; Rachel Chikwamba

doi:10.1371/journal.pone.0159313

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Peer-reviewed

Research Article

Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3

Tsepo Lebiletsa Tsekoa,

Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa
⨯
Therese Lotter-Stark,

Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa
⨯
Sindisiwe Buthelezi,

Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa
⨯
Ereck Chakauya,

Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa
⨯
Stoyan H. Stoychev,

Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa
⨯
Claude Sabeta,

Affiliation ARC-Onderstepoort Veterinary Institute, Onderstepoort, South Africa
⨯
Wonderful Shumba,

Affiliation ARC-Onderstepoort Veterinary Institute, Onderstepoort, South Africa
⨯
Baby Phahladira,

Affiliation ARC-Onderstepoort Veterinary Institute, Onderstepoort, South Africa
⨯
Steve Hume,

Affiliation Kentucky Bioprocessing, Owensboro, Kentucky, United States
⨯
Josh Morton,

Affiliation Kentucky Bioprocessing, Owensboro, Kentucky, United States
⨯
Charles E. Rupprecht,

Affiliation The Wistar Institute, Philadelphia, Pennsylvania, United States
⨯
Herta Steinkellner,

Affiliation Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria
⨯
Michael Pauly,

Affiliation Mapp Biopharmaceutical, San Diego, California, United States
⨯
Larry Zeitlin,

Affiliation Mapp Biopharmaceutical, San Diego, California, United States
⨯
Kevin Whaley,

Affiliation Mapp Biopharmaceutical, San Diego, California, United States
⨯
[ ... ],
Rachel Chikwamba

* E-mail: rchikwamba@csir.co.za

Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa
⨯
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Efficient In Vitro and In Vivo Activity of Glyco-Engineered Plant-Produced Rabies Monoclonal Antibodies E559 and 62-71-3

Tsepo Lebiletsa Tsekoa,
Therese Lotter-Stark,
Sindisiwe Buthelezi,
Ereck Chakauya,
Stoyan H. Stoychev,
Claude Sabeta,
Wonderful Shumba,
Baby Phahladira,
Steve Hume,
Josh Morton

Published: July 18, 2016
https://doi.org/10.1371/journal.pone.0159313

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Rabies virus
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Glycosylation
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Antibodies
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