The Cost of Relapsing-Remitting Multiple Sclerosis Patients Who Develop Neutralizing Antibodies during Interferon Beta Therapy

Damiano Paolicelli; Sergio Iannazzo; Laura Santoni; Antonio Iaffaldano; Valentina Di Lecce; Alessia Manni; Vito Lavolpe; Carla Tortorella; Mariangela D'Onghia; Vita Direnzo; Elisa Puma; Maria Trojano

doi:10.1371/journal.pone.0159214

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Open Access

Peer-reviewed

Research Article

The Cost of Relapsing-Remitting Multiple Sclerosis Patients Who Develop Neutralizing Antibodies during Interferon Beta Therapy

Damiano Paolicelli ,

* E-mail: damiano.paolicelli@uniba.it

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy

http://orcid.org/0000-0002-8645-1763

⨯
Sergio Iannazzo,

Affiliation SIHS Health Economics Consulting, Torino, Italia
⨯
Laura Santoni,

Affiliation Biogen Italia, Milano, Italia
⨯
Antonio Iaffaldano,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Valentina Di Lecce,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Alessia Manni,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Vito Lavolpe,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Carla Tortorella,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Mariangela D'Onghia,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Vita Direnzo,

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯
Elisa Puma,

Affiliation Biogen Italia, Milano, Italia
⨯
Maria Trojano

Affiliation Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
⨯

The Cost of Relapsing-Remitting Multiple Sclerosis Patients Who Develop Neutralizing Antibodies during Interferon Beta Therapy

Damiano Paolicelli,
Sergio Iannazzo,
Laura Santoni,
Antonio Iaffaldano,
Valentina Di Lecce,
Alessia Manni,
Vito Lavolpe,
Carla Tortorella,
Mariangela D'Onghia,
Vita Direnzo

Published: July 8, 2016
https://doi.org/10.1371/journal.pone.0159214

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