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Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype
- Isobel J. Whitehouse ,
- Deborah Brown ,
- Herbert Baybutt,
- Abigail B. Diack,
- Katherine A. B. Kellett,
- Pedro Piccardo,
- Jean C. Manson ,
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Nigel M. Hooper
* E-mail: jean.manson@roslin.ed.ac.uk (JM); nigel.hooper@manchester.ac.uk (NH)
Affiliation Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom
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http://orcid.org/0000-0002-5811-3484
Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype
- Isobel J. Whitehouse,
- Deborah Brown,
- Herbert Baybutt,
- Abigail B. Diack,
- Katherine A. B. Kellett,
- Pedro Piccardo,
- Jean C. Manson,
- Nigel M. Hooper
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- Published: July 22, 2016
- https://doi.org/10.1371/journal.pone.0159119