Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension

Csaba Galambos; Angela D. Minic; Douglas Bush; Dominique Nguyen; Blair Dodson; Gregory Seedorf; Steven H. Abman

doi:10.1371/journal.pone.0159005

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Peer-reviewed

Research Article

Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension

Csaba Galambos ,

* E-mail: csaba.galambos@childrenscolorado.org

Affiliations Departments of Pathology and Laboratory Medicine, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America, The Pediatric Heart Lung Center, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America
⨯
Angela D. Minic,

Affiliations Departments of Pathology and Laboratory Medicine, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America, The Pediatric Heart Lung Center, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America
⨯
Douglas Bush,

Affiliations Pediatrics, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America, The Pediatric Heart Lung Center, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America
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Dominique Nguyen,

Affiliation University of Notre Dame, South Bend, Indiana, United States of America
⨯
Blair Dodson,

Affiliations Pediatric Surgery, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America, The Pediatric Heart Lung Center, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America
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Gregory Seedorf,

Affiliation The Pediatric Heart Lung Center, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America
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Steven H. Abman

Affiliations Pediatrics, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America, The Pediatric Heart Lung Center, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, United States of America
⨯

Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension

Csaba Galambos,
Angela D. Minic,
Douglas Bush,
Dominique Nguyen,
Blair Dodson,
Gregory Seedorf,
Steven H. Abman

Published: August 3, 2016
https://doi.org/10.1371/journal.pone.0159005

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