Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle

Alexandra Rieger; Elisabeth Kemter; Sudhir Kumar; Bastian Popper; Bernhard Aigner; Eckhard Wolf; Rüdiger Wanke; Andreas Blutke

doi:10.1371/journal.pone.0158977

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Peer-reviewed

Research Article

Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3^L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle

Alexandra Rieger,

Affiliation Institute of Veterinary Pathology at the Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, Munich, Germany
⨯
Elisabeth Kemter,

Affiliation Chair for Molecular Animal Breeding and Biotechnology and Laboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany
⨯
Sudhir Kumar,

Affiliation Chair for Molecular Animal Breeding and Biotechnology and Laboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany
⨯
Bastian Popper,

Affiliation Department of Anatomy and Cell Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Munich, Germany
⨯
Bernhard Aigner,

Affiliation Chair for Molecular Animal Breeding and Biotechnology and Laboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany
⨯
Eckhard Wolf,

Affiliations Chair for Molecular Animal Breeding and Biotechnology and Laboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany, German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Neuherberg, Germany
⨯
Rüdiger Wanke,

Affiliation Institute of Veterinary Pathology at the Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, Munich, Germany
⨯
Andreas Blutke

* E-mail: blutke@patho.vetmed.uni-muenchen.de

Affiliation Institute of Veterinary Pathology at the Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, Munich, Germany
⨯

Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3^L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle

Alexandra Rieger,
Elisabeth Kemter,
Sudhir Kumar,
Bastian Popper,
Bernhard Aigner,
Eckhard Wolf,
Rüdiger Wanke,
Andreas Blutke

Published: July 15, 2016
https://doi.org/10.1371/journal.pone.0158977

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