A Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping Enzyme

Open Access

Peer-reviewed

Research Article

Kristen M. Bullard-Feibelman,

Affiliation Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
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Benjamin P. Fuller,

Affiliation Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
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Brian J. Geiss

* E-mail: Brian.Geiss@colostate.edu

Affiliations Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America, School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, United States of America
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Chikungunya virus
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Chikungunya infection
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Fluorescence polarization
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Fluorescence imaging
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Small molecules
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Size-exclusion chromatography
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Transfer RNA
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Enzyme inhibitors
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