Low Serum Complement C3 Levels at Diagnosis of Renal ANCA-Associated Vasculitis Is Associated with Poor Prognosis

Jean-François Augusto; Virginie Langs; Julien Demiselle; Christian Lavigne; Benoit Brilland; Agnès Duveau; Caroline Poli; Alain Chevailler; Anne Croue; Frederic Tollis; Johnny Sayegh; Jean-François Subra

doi:10.1371/journal.pone.0158871

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Open Access

Peer-reviewed

Research Article

Low Serum Complement C3 Levels at Diagnosis of Renal ANCA-Associated Vasculitis Is Associated with Poor Prognosis

Jean-François Augusto ,

* E-mail: jfaugusto@chu-angers.fr

Affiliations LUNAM Université, Angers, France, Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯
Virginie Langs,

Affiliation Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯
Julien Demiselle,

Affiliation Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯
Christian Lavigne,

Affiliation Université Angers, CHU Angers, Service de Médecine Interne, Angers, France
⨯
Benoit Brilland,

Affiliation Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯
Agnès Duveau,

Affiliation Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯
Caroline Poli,

Affiliations LUNAM Université, Angers, France, Université d’Angers, CHU Angers, Laboratoire d’Immunologie, Angers, France
⨯
Alain Chevailler,

Affiliations LUNAM Université, Angers, France, Université d’Angers, CHU Angers, Laboratoire d’Immunologie, Angers, France
⨯
Anne Croue,

Affiliation Université Angers, CHU Angers, Département de Pathologie Cellulaire et Tissulaire, Angers, France
⨯
Frederic Tollis,

Affiliation Diaverum Dialysis Center, Angers, France
⨯
Johnny Sayegh,

Affiliation Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯
Jean-François Subra

Affiliations LUNAM Université, Angers, France, Université Angers, CHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France
⨯

Low Serum Complement C3 Levels at Diagnosis of Renal ANCA-Associated Vasculitis Is Associated with Poor Prognosis

Jean-François Augusto,
Virginie Langs,
Julien Demiselle,
Christian Lavigne,
Benoit Brilland,
Agnès Duveau,
Caroline Poli,
Alain Chevailler,
Anne Croue,
Frederic Tollis

Published: July 8, 2016
https://doi.org/10.1371/journal.pone.0158871

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Complement system
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Biopsy
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Renal analysis
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Histology
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Prognosis
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Vasculitis
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Renal system
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Immunofluorescence
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