Recombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review and Meta-Analysis

• Mei-Xue Dong ,

  Contributed equally to this work with: Mei-Xue Dong, Qing-Chuan Hu, Peng Shen, Jun-Xi Pan

  Affiliations Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

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• Qing-Chuan Hu ,

  Contributed equally to this work with: Mei-Xue Dong, Qing-Chuan Hu, Peng Shen, Jun-Xi Pan

  Affiliation Chongqing Key Laboratory of Neurobiology, Chongqing, China

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• Peng Shen ,

  Contributed equally to this work with: Mei-Xue Dong, Qing-Chuan Hu, Peng Shen, Jun-Xi Pan

  Affiliation Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Jun-Xi Pan ,

  Contributed equally to this work with: Mei-Xue Dong, Qing-Chuan Hu, Peng Shen, Jun-Xi Pan

  Affiliation Chongqing Key Laboratory of Neurobiology, Chongqing, China

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• You-Dong Wei,

  Affiliation Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Yi-Yun Liu,

  Affiliation Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Yi-Fei Ren,

  Affiliation Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Zi-Hong Liang,

  Affiliation Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Hai-Yang Wang,

  Affiliation Chongqing Key Laboratory of Neurobiology, Chongqing, China

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• Li-Bo Zhao,

  Affiliation Department of Neurology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China

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• Peng Xie

  * E-mail: xiepeng@cqmu.edu.cn

  Affiliations Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

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