Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

Joanna Mackie; Edina K. Szabo; Dagmar S. Urgast; Elizabeth R. Ballou; Delma S. Childers; Donna M. MacCallum; Joerg Feldmann; Alistair J. P. Brown

doi:10.1371/journal.pone.0158683

Loading metrics

Open Access

Peer-reviewed

Research Article

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

Joanna Mackie ,

* E-mail: joanna.potrykus.mackie@gmail.com

Affiliation Aberdeen Fungal Group, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, United Kingdom
⨯
Edina K. Szabo ,

Contributed equally to this work with: Edina K. Szabo, Dagmar S. Urgast

Current address: Biological Sciences, University of Calgary, 507 Campus Drive N.W., Calgary T2N 1N4, AB, Canada

Affiliation Aberdeen Fungal Group, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, United Kingdom
⨯
Dagmar S. Urgast ,

Contributed equally to this work with: Edina K. Szabo, Dagmar S. Urgast

Affiliation Trace Element Speciation Laboratory, Department of Chemistry, College of Physical Science, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, United Kingdom
⨯
Elizabeth R. Ballou,

Affiliation Aberdeen Fungal Group, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, United Kingdom
⨯
Delma S. Childers,

Affiliation Aberdeen Fungal Group, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, United Kingdom
⨯
Donna M. MacCallum,

Affiliation Aberdeen Fungal Group, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, United Kingdom
⨯
Joerg Feldmann,

Affiliation Trace Element Speciation Laboratory, Department of Chemistry, College of Physical Science, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, United Kingdom
⨯
Alistair J. P. Brown

Affiliation Aberdeen Fungal Group, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, United Kingdom
⨯

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

Joanna Mackie,
Edina K. Szabo,
Dagmar S. Urgast,
Elizabeth R. Ballou,
Delma S. Childers,
Donna M. MacCallum,
Joerg Feldmann,
Alistair J. P. Brown

Published: June 30, 2016
https://doi.org/10.1371/journal.pone.0158683

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Candida albicans
Is the Subject Area "Candida albicans" applicable to this article?

Thanks for your feedback.
Kidneys
Is the Subject Area "Kidneys" applicable to this article?

Thanks for your feedback.
Fungal genetics
Is the Subject Area "Fungal genetics" applicable to this article?

Thanks for your feedback.
Homeostasis
Is the Subject Area "Homeostasis" applicable to this article?

Thanks for your feedback.
Fungal diseases
Is the Subject Area "Fungal diseases" applicable to this article?

Thanks for your feedback.
Iron
Is the Subject Area "Iron" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Copper
Is the Subject Area "Copper" applicable to this article?

Thanks for your feedback.