Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation

Open Access

Peer-reviewed

Research Article

Todd J. Cohen ,

* E-mail: toddcohen@neurology.unc.edu

Affiliations Department of Neurology, UNC Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Brian H. Constance,

Affiliations Department of Neurology, UNC Neuroscience Center, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina, United States of America
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Andrew W. Hwang,

Affiliation Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Michael James,

Affiliation Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Chao-Xing Yuan

Affiliation Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Acetylation
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Tau protein
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Cysteine
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Lysine
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Immunoblotting
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Proteolysis
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Alzheimer's disease
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Proteases
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