Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks

Yin-ying Chen; Ya-nan Yu; Ying-ying Zhang; Bing Li; Jun Liu; Dong-feng Li; Ping Wu; Jie Wang; Zhong Wang; Yong-yan Wang

doi:10.1371/journal.pone.0158379

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Open Access

Peer-reviewed

Research Article

Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks

Yin-ying Chen,

Affiliations Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Ya-nan Yu,

Affiliation Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Ying-ying Zhang,

Affiliation Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Bing Li,

Affiliation Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Jun Liu,

Affiliation Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Dong-feng Li,

Affiliation School of Mathematical Sciences, Peking University, Beijing, China
⨯
Ping Wu,

Affiliation Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Jie Wang ,

* E-mail: jie_wang_0107@yeah.net (JW); zhonw@sina.com (ZW); wangyongyan2010@sina.cn (YYW)

Affiliation Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Zhong Wang ,

* E-mail: jie_wang_0107@yeah.net (JW); zhonw@sina.com (ZW); wangyongyan2010@sina.cn (YYW)

Affiliation Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
⨯
Yong-yan Wang

* E-mail: jie_wang_0107@yeah.net (JW); zhonw@sina.com (ZW); wangyongyan2010@sina.cn (YYW)

Affiliation Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
⨯

Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks

Yin-ying Chen,
Ya-nan Yu,
Ying-ying Zhang,
Bing Li,
Jun Liu,
Dong-feng Li,
Ping Wu,
Jie Wang,
Zhong Wang,
Yong-yan Wang

Published: July 6, 2016
https://doi.org/10.1371/journal.pone.0158379

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