Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitochondrial Damage in Human B-Lymphocytes

Open Access

Peer-reviewed

Research Article

Baikuntha Aryal,

Affiliation Laboratory of Applied Biochemistry, Division of Biotechnology Review and Research III, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, 20993, United States of America
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V. Ashutosh Rao

* E-mail: ashutosh.rao@fda.hhs.gov

Affiliation Laboratory of Applied Biochemistry, Division of Biotechnology Review and Research III, Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, 20993, United States of America
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Mitochondria
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Lymphocytes
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Apoptosis
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Mitochondrial membrane
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Small interfering RNA
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Transfection
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Lipid peroxidation
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Superoxides
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