Estimating Exceptionally Rare Germline and Somatic Mutation Frequencies via Next Generation Sequencing

• Jordan Eboreime ,

  Contributed equally to this work with: Jordan Eboreime, Soo-Kung Choi

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089–2910, United States of America

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• Soo-Kung Choi ,

  Contributed equally to this work with: Jordan Eboreime, Soo-Kung Choi

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089–2910, United States of America

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• Song-Ro Yoon,

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089–2910, United States of America

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• Norman Arnheim ,

  * E-mail: arnheim@usc.edu (NA); petercal@usc.edu (PC)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089–2910, United States of America

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• Peter Calabrese

  * E-mail: arnheim@usc.edu (NA); petercal@usc.edu (PC)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089–2910, United States of America

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