How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections?

Carolin Vegvari; Christoforos Hadjichrysanthou; Emilie Cauët; Emma Lawrence; Anne Cori; Frank de Wolf; Roy M. Anderson

doi:10.1371/journal.pone.0158237

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Research Article

How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections?

Carolin Vegvari ,

Contributed equally to this work with: Carolin Vegvari, Christoforos Hadjichrysanthou, Emilie Cauët, Emma Lawrence

* E-mail: c.vegvari@imperial.ac.uk

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Christoforos Hadjichrysanthou ,

Contributed equally to this work with: Carolin Vegvari, Christoforos Hadjichrysanthou, Emilie Cauët, Emma Lawrence

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Emilie Cauët ,

Contributed equally to this work with: Carolin Vegvari, Christoforos Hadjichrysanthou, Emilie Cauët, Emma Lawrence

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Emma Lawrence ,

Contributed equally to this work with: Carolin Vegvari, Christoforos Hadjichrysanthou, Emilie Cauët, Emma Lawrence

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Anne Cori,

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Frank de Wolf,

Affiliation Janssen Prevention Center, Leiden, The Netherlands
⨯
Roy M. Anderson

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯

How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections?

Carolin Vegvari,
Christoforos Hadjichrysanthou,
Emilie Cauët,
Emma Lawrence,
Anne Cori,
Frank de Wolf,
Roy M. Anderson

Published: July 1, 2016
https://doi.org/10.1371/journal.pone.0158237

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