Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren’s Disease

• Kerstin Becker,

  Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, Cologne, Germany

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• Sabine Siegert,

  Affiliation Cologne Center for Genomics, University of Cologne, Cologne, Germany

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• Mohammad Reza Toliat,

  Affiliation Cologne Center for Genomics, University of Cologne, Cologne, Germany

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• Juanjiangmeng Du,

  Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, Cologne, Germany

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• Ramona Casper,

  Affiliation Cologne Center for Genomics, University of Cologne, Cologne, Germany

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• Guido H. Dolmans,

  Affiliation University of Groningen and University Medical Center Groningen, Dept. of Plastic Surgery, Groningen, the Netherlands

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• Paul M. Werker,

  Affiliation University of Groningen and University Medical Center Groningen, Dept. of Plastic Surgery, Groningen, the Netherlands

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• Sigrid Tinschert,

  Affiliations Div. of Human Genetics and Dept. of Dermatology, Medical University of Innsbruck, Innsbruck, Austria, Inst. of Clinical Genetics, Dresden University of Technology, Dresden, Germany

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• Andre Franke,

  Affiliation Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, University Hospital Schleswig-Holstein, Kiel, Germany

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• Christian Gieger,

  Affiliations Research Unit Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Epidemiologie II, Helmholtz Zentrum München, Neuherberg, Germany, German Center for Diabetes Research, Neuherberg, Germany

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• Konstantin Strauch,

  Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany

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• Michael Nothnagel,

  Affiliation Cologne Center for Genomics, University of Cologne, Cologne, Germany

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• Peter Nürnberg,

  Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, Cologne, Germany

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• Hans Christian Hennies ,

  * E-mail: h.hennies@uni-koeln.de

  Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, Cologne, Germany, Div. of Human Genetics and Dept. of Dermatology, Medical University of Innsbruck, Innsbruck, Austria, Dept. of Biological Sciences, University of Huddersfield, Huddersfield, United Kingdom

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• German Dupuytren Study Group

  ¶The names of the members of the German Dupuytren Study Group are listed in the Acknowledgments.

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