Hypoxic Stress Induced by Hydralazine Leads to a Loss of Blood-Brain Barrier Integrity and an Increase in Efflux Transporter Activity

Open Access

Peer-reviewed

Research Article

Morgane Chatard,

Affiliations Université de Lyon, UJM-Saint-Etienne, SNA-EPIS, EA4607, F-42023, Saint-Etienne, France, Université de Lyon, UJM-Saint-Etienne, INSERM, SAINBIOSE U1089 Team DVH, F-42023, Saint-Etienne, France
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Clémentine Puech,

Affiliation Université de Lyon, UJM-Saint-Etienne, INSERM, SAINBIOSE U1089 Team DVH, F-42023, Saint-Etienne, France
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Frederic Roche ,

Contributed equally to this work with: Frederic Roche, Nathalie Perek

* E-mail: frederic.roche@univ-st-etienne.fr

Affiliation Université de Lyon, UJM-Saint-Etienne, SNA-EPIS, EA4607, F-42023, Saint-Etienne, France
⨯
Nathalie Perek

Contributed equally to this work with: Frederic Roche, Nathalie Perek

Affiliation Université de Lyon, UJM-Saint-Etienne, INSERM, SAINBIOSE U1089 Team DVH, F-42023, Saint-Etienne, France
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Hypoxia
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Medical hypoxia
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Aquatic hypoxia
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Blood-brain barrier
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Permeability
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Cytotoxicity
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Endothelial cells
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Cell immortalization
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