The Aberrant DNA Methylation Profile of Human Induced Pluripotent Stem Cells Is Connected to the Reprogramming Process and Is Normalized During In Vitro Culture

Open Access

Peer-reviewed

Research Article

Lenka Tesarova ,

* E-mail: lenkatesarov@gmail.com

Affiliations Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic, International Clinical Research Center, St. Anne’s University Hospital Brno, Brno, Czech Republic
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Pavel Simara,

Affiliations Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic, International Clinical Research Center, St. Anne’s University Hospital Brno, Brno, Czech Republic
⨯
Stanislav Stejskal,

Affiliation Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic
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Irena Koutna

Affiliations Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic, International Clinical Research Center, St. Anne’s University Hospital Brno, Brno, Czech Republic
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DNA methylation
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Gene expression
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Cell differentiation
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Pluripotency
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Polymerase chain reaction
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Fibroblasts
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DNA
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Epigenetics
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