Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels

Emmanuelle Cordeau; Carine Arnaudguilhem; Brice Bouyssiere; Agnès Hagège; Jean Martinez; Gilles Subra; Sonia Cantel; Christine Enjalbal

doi:10.1371/journal.pone.0157943

Loading metrics

Open Access

Peer-reviewed

Research Article

Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels

Emmanuelle Cordeau,

Affiliation Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, Place Eugène Bataillon, 34095 Montpellier cedex 5, France
⨯
Carine Arnaudguilhem,

Affiliation Laboratoire de Chimie Analytique Bio-inorganique et Environnement LCABIE-IPREM, UMR 5254, Hélioparc, 2 av. Pr. Angot, 64053 Pau, France
⨯
Brice Bouyssiere,

Affiliation Laboratoire de Chimie Analytique Bio-inorganique et Environnement LCABIE-IPREM, UMR 5254, Hélioparc, 2 av. Pr. Angot, 64053 Pau, France
⨯
Agnès Hagège,

Affiliation Institute of Analytical Sciences (ISA), UMR 5280, CNRS, Université Lyon 1, 5 rue de la Doua, 69100 Villeurbanne, France
⨯
Jean Martinez,

Affiliation Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, Place Eugène Bataillon, 34095 Montpellier cedex 5, France
⨯
Gilles Subra,

Affiliation Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, Place Eugène Bataillon, 34095 Montpellier cedex 5, France
⨯
Sonia Cantel,

Affiliation Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, Place Eugène Bataillon, 34095 Montpellier cedex 5, France
⨯
Christine Enjalbal

* E-mail: enjalbal@univ-montp2.fr

Affiliation Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, Place Eugène Bataillon, 34095 Montpellier cedex 5, France

http://orcid.org/0000-0003-4646-4583

⨯

Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels

Emmanuelle Cordeau,
Carine Arnaudguilhem,
Brice Bouyssiere,
Agnès Hagège,
Jean Martinez,
Gilles Subra,
Sonia Cantel,
Christine Enjalbal

Published: June 23, 2016
https://doi.org/10.1371/journal.pone.0157943

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Selenium
Is the Subject Area "Selenium" applicable to this article?

Thanks for your feedback.
Isotopes
Is the Subject Area "Isotopes" applicable to this article?

Thanks for your feedback.
Elution
Is the Subject Area "Elution" applicable to this article?

Thanks for your feedback.
Signal peptides
Is the Subject Area "Signal peptides" applicable to this article?

Thanks for your feedback.
Chemical elements
Is the Subject Area "Chemical elements" applicable to this article?

Thanks for your feedback.
Chromatographic techniques
Is the Subject Area "Chromatographic techniques" applicable to this article?

Thanks for your feedback.
Organic solvents
Is the Subject Area "Organic solvents" applicable to this article?

Thanks for your feedback.
Pharmacology
Is the Subject Area "Pharmacology" applicable to this article?

Thanks for your feedback.