Multiparametric Classification of Skin from Osteogenesis Imperfecta Patients and Controls by Quantitative Magnetic Resonance Microimaging

Beth G. Ashinsky; Kenneth W. Fishbein; Erin M. Carter; Ping-Chang Lin; Nancy Pleshko; Cathleen L. Raggio; Richard G. Spencer

doi:10.1371/journal.pone.0157891

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Peer-reviewed

Research Article

Multiparametric Classification of Skin from Osteogenesis Imperfecta Patients and Controls by Quantitative Magnetic Resonance Microimaging

Beth G. Ashinsky ,

Contributed equally to this work with: Beth G. Ashinsky, Kenneth W. Fishbein

Affiliation Laboratory of Clinical Investigation, Magnetic Resonance Imaging and Spectroscopy Section, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Kenneth W. Fishbein ,

Contributed equally to this work with: Beth G. Ashinsky, Kenneth W. Fishbein

Affiliation Laboratory of Clinical Investigation, Magnetic Resonance Imaging and Spectroscopy Section, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Erin M. Carter,

Affiliation Kathryn O. and Alan C. Greenberg Center for Skeletal Dysplasias, Hospital for Special Surgery, New York, New York, United States of America
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Ping-Chang Lin,

Affiliation Core Imaging Facility for Small Animals, GRU Cancer Center, Augusta University Augusta, Georiga, United States of America
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Nancy Pleshko,

Affiliation Department of Bioengineering, College of Engineering, Temple University, Philadelphia, United States of America
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Cathleen L. Raggio,

Affiliations Kathryn O. and Alan C. Greenberg Center for Skeletal Dysplasias, Hospital for Special Surgery, New York, New York, United States of America, Department of Orthopaedics, Hospital for Special Surgery, New York, New York, United States of America
⨯
Richard G. Spencer

* E-mail: spencer@helix.nih.gov

Affiliation Laboratory of Clinical Investigation, Magnetic Resonance Imaging and Spectroscopy Section, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯

Multiparametric Classification of Skin from Osteogenesis Imperfecta Patients and Controls by Quantitative Magnetic Resonance Microimaging

Beth G. Ashinsky,
Kenneth W. Fishbein,
Erin M. Carter,
Ping-Chang Lin,
Nancy Pleshko,
Cathleen L. Raggio,
Richard G. Spencer

Published: July 14, 2016
https://doi.org/10.1371/journal.pone.0157891

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Osteogenesis imperfecta
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Magnetic resonance imaging
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Collagens
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Biopsy
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Dermis
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Histology
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Skin
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Multivariate analysis
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