Cortical Dopamine Transmission as Measured with the [11C]FLB 457 – Amphetamine PET Imaging Paradigm Is Not Influenced by COMT Genotype

Open Access

Peer-reviewed

Research Article

Cortical Dopamine Transmission as Measured with the [¹¹C]FLB 457 – Amphetamine PET Imaging Paradigm Is Not Influenced by COMT Genotype

Rajesh Narendran ,

* E-mail: narendranr@upmc.edu

Affiliations Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America, Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
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Divya Tumuluru,

Affiliation Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
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Maureen A. May,

Affiliation Allegheny Health Network Cancer Genetics Program, Pittsburgh, Pennsylvania, 15213, United States of America
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Kodavali V. Chowdari,

Affiliation Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
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Michael L. Himes,

Affiliation Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
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Kelli Fasenmyer,

Affiliation Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
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W. Gordon Frankle,

Affiliation Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
⨯
Vishwajit L. Nimgaonkar

Affiliations Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America, Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States of America
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Dopamine
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Amphetamines
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Positron emission tomography
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Prefrontal cortex
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Receptor potentials
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Cerebellum
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Dopaminergics
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Magnetic resonance imaging
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