Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

• Westa Domanova ,

  Contributed equally to this work with: Westa Domanova, James Krycer

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Physics, The University of Sydney, Sydney, NSW 2006, Australia

  http://orcid.org/0000-0003-3215-4883

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• James Krycer ,

  Contributed equally to this work with: Westa Domanova, James Krycer

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia

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• Rima Chaudhuri,

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia

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• Pengyi Yang,

  Affiliation National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, NC 27709, United States of America

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• Fatemeh Vafaee,

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Mathematics and Statistics, The University of Sydney, Sydney, NSW 2006, Australia

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• Daniel Fazakerley,

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia

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• Sean Humphrey,

  Affiliation Department of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, 82152, Germany

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• David James ,

  * E-mail: zdenka.kuncic@sydney.edu.au (ZK); david.james@sydney.edu.au (DJ)

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Life and Environmental Sciences, The University of Sydney, Sydney, NSW 2006, Australia, Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia

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• Zdenka Kuncic

  * E-mail: zdenka.kuncic@sydney.edu.au (ZK); david.james@sydney.edu.au (DJ)

  Affiliations Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia, School of Physics, The University of Sydney, Sydney, NSW 2006, Australia

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