Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function

Open Access

Peer-reviewed

Research Article

Calvin H. Yeh,

Affiliation Departments of Medicine and Biochemistry and Biomedical Sciences, McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada
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Alan R. Stafford,

Affiliation Departments of Medicine and Biochemistry and Biomedical Sciences, McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada
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Beverly A. Leslie,

Affiliation Departments of Medicine and Biochemistry and Biomedical Sciences, McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada
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James C. Fredenburgh,

Affiliation Departments of Medicine and Biochemistry and Biomedical Sciences, McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada
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Jeffrey I. Weitz

* E-mail: weitzj@taari.ca

Affiliation Departments of Medicine and Biochemistry and Biomedical Sciences, McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada
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Thrombin
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Fibrin
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Amperometry
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Allosteric regulation
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Binding analysis
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Fibrinogen
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Regression analysis
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Small molecules
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