Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension

Yuan-yuan Qu; Jing Hui; La-mei Wang; Na Tang; Hua Zhong; Yong-min Liu; Zhen Li; Qian Feng; Fang He

doi:10.1371/journal.pone.0157456

Loading metrics

Open Access

Peer-reviewed

Research Article

Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension

Yuan-yuan Qu ,

Contributed equally to this work with: Yuan-yuan Qu, Jing Hui

Affiliations Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China, Department of Emergency and critical care medicine, the First Affiliated Hospital of Medical College of Shihezi University, Shihezi, 832008, China
⨯
Jing Hui ,

Contributed equally to this work with: Yuan-yuan Qu, Jing Hui

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯
La-mei Wang,

Affiliation Centre of Medical Functional Experiments, Medical College of Shihezi University, Shihezi, China
⨯
Na Tang,

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯
Hua Zhong,

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯
Yong-min Liu,

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯
Zhen Li,

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯
Qian Feng,

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯
Fang He

* E-mail: fangf2002shz@126.com

Affiliation Department of Pathophysiology/Key Laboratory of Education Ministry of Xinjiang Endemic and Ethnic Diseases, Medical College of Shihezi University, Shihezi, China
⨯

Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension

Yuan-yuan Qu,
Jing Hui,
La-mei Wang,
Na Tang,
Hua Zhong,
Yong-min Liu,
Zhen Li,
Qian Feng,
Fang He

Published: July 8, 2016
https://doi.org/10.1371/journal.pone.0157456

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Aorta
Is the Subject Area "Aorta" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.
Hypertension
Is the Subject Area "Hypertension" applicable to this article?

Thanks for your feedback.
Plasma proteins
Is the Subject Area "Plasma proteins" applicable to this article?

Thanks for your feedback.
Computer software
Is the Subject Area "Computer software" applicable to this article?

Thanks for your feedback.
Blood pressure
Is the Subject Area "Blood pressure" applicable to this article?

Thanks for your feedback.
Renin-angiotensin system
Is the Subject Area "Renin-angiotensin system" applicable to this article?

Thanks for your feedback.
Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.