Amphipathic β2,2-Amino Acid Derivatives Suppress Infectivity and Disrupt the Intracellular Replication Cycle of Chlamydia pneumoniae

Open Access

Peer-reviewed

Research Article

Amphipathic β^2,2-Amino Acid Derivatives Suppress Infectivity and Disrupt the Intracellular Replication Cycle of Chlamydia pneumoniae

Leena Hanski ,

Contributed equally to this work with: Leena Hanski, Dominik Ausbacher

Affiliation Pharmaceutical Design and Discovery Research Group, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki (UHEL), Helsinki, Finland
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Dominik Ausbacher ,

Contributed equally to this work with: Leena Hanski, Dominik Ausbacher

Affiliation Natural Products and Medicinal Chemistry Research Group, Department of Pharmacy, Faculty of Health Sciences, UiT – The Arctic University of Norway, Tromsø, Norway
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Terttu M. Tiirola,

Affiliation Pharmaceutical Design and Discovery Research Group, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki (UHEL), Helsinki, Finland
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Morten B. Strøm,

Affiliation Natural Products and Medicinal Chemistry Research Group, Department of Pharmacy, Faculty of Health Sciences, UiT – The Arctic University of Norway, Tromsø, Norway
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Pia M. Vuorela

* E-mail: pia.vuorela@helsinki.fi

Affiliation Pharmaceutical Design and Discovery Research Group, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki (UHEL), Helsinki, Finland
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Chlamydophila pneumoniae
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Chlamydia infection
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Cell membranes
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Vacuoles
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Intracellular pathogens
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Host cells
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Chlamydia
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Respiratory infections
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