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Open Access
Peer-reviewed
Research Article
Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis
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Yun-Cheng Lv ,
Contributed equally to this work with: Yun-Cheng Lv, Yan-Yan Tang, Ping Zhang
Affiliations Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China, Laboratory of Clinical Anatomy, University of South China, Hengyang, 421001, China
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Yan-Yan Tang ,
Contributed equally to this work with: Yun-Cheng Lv, Yan-Yan Tang, Ping Zhang
Affiliations The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health and The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, 410013, China, Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Ping Zhang ,
Contributed equally to this work with: Yun-Cheng Lv, Yan-Yan Tang, Ping Zhang
Affiliations School of Electronics and Information Engineering, Hunan University of Science and Engineering, Yongzhou, Hunan, 425100, China, School of Information Science and Engineering, Central South University, Changsha, Hunan, 410000, China
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Wei Wan,
Affiliation Laboratory of Clinical Anatomy, University of South China, Hengyang, 421001, China
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Feng Yao,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Ping-Ping He,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Wei Xie,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Zhong-Cheng Mo,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Jin-Feng Shi,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Jian-Feng Wu,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Juan Peng,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Dan Liu,
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Francisco S. Cayabyab,
Affiliation Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada
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Xi-Long Zheng,
Affiliation Department of Biochemistry and Molecular Biology, The Libin Cardiovascular Institute of Alberta, The University of Calgary, Health Sciences Center, 3330 Hospital Dr NW, Calgary, Alberta, T2N 4N1, Canada
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Xiang-Yang Tang,
Affiliations Laboratory of Clinical Anatomy, University of South China, Hengyang, 421001, China, Department of Radiology and Imaging Sciences, Emory University School of Medicine, WCI Suite C5018, 1701 Uppergate Drive, Atlanta, GA, 30322, United States of America
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Xin-Ping Ouyang ,
* E-mail: tangchaoke@qq.com (CKT); y1655@163.com (XPOY)
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Chao-Ke Tang
* E-mail: tangchaoke@qq.com (CKT); y1655@163.com (XPOY)
Affiliation Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China
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Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis
- Yun-Cheng Lv,
- Yan-Yan Tang,
- Ping Zhang,
- Wei Wan,
- Feng Yao,
- Ping-Ping He,
- Wei Xie,
- Zhong-Cheng Mo,
- Jin-Feng Shi,
- Jian-Feng Wu
- Published: June 13, 2016
- https://doi.org/10.1371/journal.pone.0157265