Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers and PD-1 Expression on Lymphocytes in Canine Oral Melanoma

Naoya Maekawa; Satoru Konnai; Tomohiro Okagawa; Asami Nishimori; Ryoyo Ikebuchi; Yusuke Izumi; Satoshi Takagi; Yumiko Kagawa; Chie Nakajima; Yasuhiko Suzuki; Yukinari Kato; Shiro Murata; Kazuhiko Ohashi

doi:10.1371/journal.pone.0157176

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Open Access

Peer-reviewed

Research Article

Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers and PD-1 Expression on Lymphocytes in Canine Oral Melanoma

Naoya Maekawa,

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Satoru Konnai,

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Tomohiro Okagawa,

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Asami Nishimori,

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Ryoyo Ikebuchi,

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Yusuke Izumi,

Affiliation Veterinary Teaching Hospital, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Satoshi Takagi,

Affiliation Veterinary Teaching Hospital, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Yumiko Kagawa,

Affiliations North Lab, Sapporo, Japan, Department of Diagnostic Pathology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Chie Nakajima,

Affiliation Research Center for Zoonosis Control, Hokkaido University, Sapporo, Japan
⨯
Yasuhiko Suzuki,

Affiliation Research Center for Zoonosis Control, Hokkaido University, Sapporo, Japan
⨯
Yukinari Kato,

Affiliation Department of Regional Innovation, Graduate School of Medicine, Tohoku University, Sendai, Japan
⨯
Shiro Murata,

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯
Kazuhiko Ohashi

* E-mail: okazu@vetmed.hokudai.ac.jp

Affiliation Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
⨯

Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers and PD-1 Expression on Lymphocytes in Canine Oral Melanoma

Naoya Maekawa,
Satoru Konnai,
Tomohiro Okagawa,
Asami Nishimori,
Ryoyo Ikebuchi,
Yusuke Izumi,
Satoshi Takagi,
Yumiko Kagawa,
Chie Nakajima,
Yasuhiko Suzuki

Published: June 8, 2016
https://doi.org/10.1371/journal.pone.0157176

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