Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production

Christopher S. Malarkey; Claire E. Gustafson; Jessica F. Saifee; Raul M. Torres; Mair E. A. Churchill; Edward N. Janoff

doi:10.1371/journal.pone.0157157

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Research Article

Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production

Christopher S. Malarkey ,

Contributed equally to this work with: Christopher S. Malarkey, Claire E. Gustafson

Current address: Department of Pharmaceutical Sciences, School of Pharmacy, Regis University, 3333 Regis Boulevard, H-28, Denver, CO, 80221–1099, United States of America

Affiliation Department of Pharmacology and the Program in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, CO, 80045, United States of America
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Claire E. Gustafson ,

Contributed equally to this work with: Christopher S. Malarkey, Claire E. Gustafson

Current address: Department of Medicine, Stanford University, Palo Alto, CA, 94304, United States of America

Affiliation Mucosal and Vaccine Research Program Colorado (MAVRC), Department of Medicine and the Program in Immunology, University of Colorado School of Medicine, Aurora, CO, 80045, United States of America, and Denver Veterans Affairs Medical Center, Denver, CO, 80220, United States of America
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Jessica F. Saifee,

Current address: 33 Dover Rd, Wellesley, MA, 02482, United States of America

Affiliation Department of Pharmacology and the Program in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, CO, 80045, United States of America
⨯
Raul M. Torres,

Affiliation Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, 80045, United States of America
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Mair E. A. Churchill ,

* E-mail: Mair.Churchill@ucdenver.edu

¶‡ These authors also contributed equally to this work.

Affiliation Department of Pharmacology and the Program in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, CO, 80045, United States of America

http://orcid.org/0000-0003-0862-235X

⨯
Edward N. Janoff

¶‡ These authors also contributed equally to this work.

Affiliation Mucosal and Vaccine Research Program Colorado (MAVRC), Department of Medicine and the Program in Immunology, University of Colorado School of Medicine, Aurora, CO, 80045, United States of America, and Denver Veterans Affairs Medical Center, Denver, CO, 80220, United States of America
⨯

Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production

Christopher S. Malarkey,
Claire E. Gustafson,
Jessica F. Saifee,
Raul M. Torres,
Mair E. A. Churchill,
Edward N. Janoff

Published: June 9, 2016
https://doi.org/10.1371/journal.pone.0157157

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