Alpha 5 Integrin Mediates Osteoarthritic Changes in Mouse Knee Joints

• Maria Elena Candela,

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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• Chao Wang,

  Affiliation School of Biomedical Engineering Science, and Health Systems, Drexel University, Philadelphia, PA, United States of America

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• Aruni T. Gunawardena,

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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• Kairui Zhang,

  Affiliations Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America, Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, China

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• Leslie Cantley,

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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• Rika Yasuhara,

  Affiliation Division of Pathology, Department of Oral Diagnosis Science, School of Dentistry, Showa University, Tokyo, Japan

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• Yu Usami,

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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• Noelle Francois,

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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• Masahiro Iwamoto,

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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• Arjan van der Flier,

  Affiliation Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Yejia Zhang,

  Affiliation Department of Physical Medicine and Rehabilitation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America

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• Ling Qin,

  Affiliation Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, United States of America

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• Lin Han,

  Affiliation School of Biomedical Engineering Science, and Health Systems, Drexel University, Philadelphia, PA, United States of America

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• Motomi Enomoto-Iwamoto

  * E-mail: iwamotom1@email.chop.edu

  Affiliation Department of Surgery, Division of Orthopaedic Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

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