Anti-EBOV GP IgGs Lacking α1-3-Galactose and Neu5Gc Prolong Survival and Decrease Blood Viral Load in EBOV-Infected Guinea Pigs

• Olivier Reynard,

  Affiliation Molecular Basis of Viral Pathogenicity, CIRI, INSERM U1111—CNRS UMR5308, Université de Lyon, Université Claude Bernard Lyon 1, Ecole Normale supérieure de Lyon, Lyon, France

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• Frédéric Jacquot,

  Affiliation Inserm-Jean Mérieux BSL4 Laboratory, US003 Inserm, Lyon, France

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• Gwénaëlle Evanno,

  Affiliation Xenothera, Nantes, France

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• Hoa Le Mai,

  Affiliations INSERM, UMR 1064, Nantes, France, CHU de Nantes, ITUN, Nantes, France, Université de Nantes, Nantes, France

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• Apolline Salama,

  Affiliation Xenothera, Nantes, France

  http://orcid.org/0000-0002-3157-0749

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• Bernard Martinet,

  Affiliations INSERM, UMR 1064, Nantes, France, CHU de Nantes, ITUN, Nantes, France, Université de Nantes, Nantes, France

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• Odile Duvaux,

  Affiliation Xenothera, Nantes, France

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• Jean-Marie Bach,

  Affiliations Xenothera, Nantes, France, IECM, EA4644 Université de Nantes, ONIRIS, USC1383 INRA, Nantes, France

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• Sophie Conchon,

  Affiliations INSERM, UMR 1064, Nantes, France, CHU de Nantes, ITUN, Nantes, France, Université de Nantes, Nantes, France

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• Jean-Paul Judor,

  Affiliations INSERM, UMR 1064, Nantes, France, CHU de Nantes, ITUN, Nantes, France, Université de Nantes, Nantes, France

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• Andrea Perota,

  Affiliation Avantea, Laboratory of Reproductive Technologies, Cremona, Italy

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• Irina Lagutina,

  Affiliation Avantea, Laboratory of Reproductive Technologies, Cremona, Italy

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• Roberto Duchi,

  Affiliation Avantea, Laboratory of Reproductive Technologies, Cremona, Italy

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• Giovanna Lazzari,

  Affiliations Avantea, Laboratory of Reproductive Technologies, Cremona, Italy, Avantea Foundation, Cremona, Italy

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• Ludmilla Le Berre,

  Affiliations INSERM, UMR 1064, Nantes, France, CHU de Nantes, ITUN, Nantes, France, Université de Nantes, Nantes, France

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• Hélène Perreault,

  Affiliation Chemistry Department, University of Manitoba, Winnipeg, Canada

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• Elsa Lheriteau,

  Affiliation Xenothera, Nantes, France

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• Hervé Raoul ,

  * E-mail: jean-paul.soulillou@univ-nantes.fr (JPS); viktor.volchkov@inserm.fr (VV); cesaregalli@avantea.it; herve.raoul@inserm.fr (HR)

  Affiliation Inserm-Jean Mérieux BSL4 Laboratory, US003 Inserm, Lyon, France

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• Viktor Volchkov ,

  * E-mail: jean-paul.soulillou@univ-nantes.fr (JPS); viktor.volchkov@inserm.fr (VV); cesaregalli@avantea.it; herve.raoul@inserm.fr (HR)

  Affiliation Molecular Basis of Viral Pathogenicity, CIRI, INSERM U1111—CNRS UMR5308, Université de Lyon, Université Claude Bernard Lyon 1, Ecole Normale supérieure de Lyon, Lyon, France

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• Cesare Galli ,

  * E-mail: jean-paul.soulillou@univ-nantes.fr (JPS); viktor.volchkov@inserm.fr (VV); cesaregalli@avantea.it; herve.raoul@inserm.fr (HR)

  Affiliations Avantea, Laboratory of Reproductive Technologies, Cremona, Italy, Avantea Foundation, Cremona, Italy, Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy

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•  [ ... ],
• Jean-Paul Soulillou

  * E-mail: jean-paul.soulillou@univ-nantes.fr (JPS); viktor.volchkov@inserm.fr (VV); cesaregalli@avantea.it; herve.raoul@inserm.fr (HR)

  Affiliations Xenothera, Nantes, France, Université de Nantes, Nantes, France

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