Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced RANKL

Open Access

Peer-reviewed

Research Article

Ali Kassem,

Affiliation Department of Molecular Periodontology, Umeå University, Umeå, Sweden
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Catharina Lindholm,

Affiliations Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition at Institute for Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Ulf H Lerner

* E-mail: ulf.lerner@umu.se

Affiliations Department of Molecular Periodontology, Umeå University, Umeå, Sweden, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition at Institute for Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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Staphylococcus aureus
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Bone resorption
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Osteoclasts
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Osteoblasts
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Macrophages
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Cytokines
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Bone marrow cells
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Gene expression
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