Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Hongmei Zhu; Jun Liu; Chenchen Cui; Yujie Song; Hengtao Ge; Linyong Hu; Qian Li; Yaping Jin; Yong Zhang

doi:10.1371/journal.pone.0156636

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Peer-reviewed

Research Article

Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Hongmei Zhu ,

Contributed equally to this work with: Hongmei Zhu, Jun Liu

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Jun Liu ,

Contributed equally to this work with: Hongmei Zhu, Jun Liu

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Chenchen Cui,

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Yujie Song,

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Hengtao Ge,

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Linyong Hu,

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Qian Li,

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Yaping Jin ,

* E-mail: yapingjin@163.com (YJ); zhangyong1956@nwsuaf.edu.cn (YZ)

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯
Yong Zhang

* E-mail: yapingjin@163.com (YJ); zhangyong1956@nwsuaf.edu.cn (YZ)

Affiliations College of Veterinary Medicine, Northwest A&F University, Yangling, 712100, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling, 712100, Shaanxi, China
⨯

Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Hongmei Zhu,
Jun Liu,
Chenchen Cui,
Yujie Song,
Hengtao Ge,
Linyong Hu,
Qian Li,
Yaping Jin,
Yong Zhang

Published: June 3, 2016
https://doi.org/10.1371/journal.pone.0156636

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