Using Clinical Trial Simulators to Analyse the Sources of Variance in Clinical Trials of Novel Therapies for Acute Viral Infections

Carolin Vegvari; Emilie Cauët; Christoforos Hadjichrysanthou; Emma Lawrence; Gerrit-Jan Weverling; Frank de Wolf; Roy M. Anderson

doi:10.1371/journal.pone.0156622

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Research Article

Using Clinical Trial Simulators to Analyse the Sources of Variance in Clinical Trials of Novel Therapies for Acute Viral Infections

Carolin Vegvari ,

Contributed equally to this work with: Carolin Vegvari, Emilie Cauët, Christoforos Hadjichrysanthou, Emma Lawrence

* E-mail: c.vegvari@imperial.ac.uk

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Emilie Cauët ,

Contributed equally to this work with: Carolin Vegvari, Emilie Cauët, Christoforos Hadjichrysanthou, Emma Lawrence

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Christoforos Hadjichrysanthou ,

Contributed equally to this work with: Carolin Vegvari, Emilie Cauët, Christoforos Hadjichrysanthou, Emma Lawrence

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Emma Lawrence ,

Contributed equally to this work with: Carolin Vegvari, Emilie Cauët, Christoforos Hadjichrysanthou, Emma Lawrence

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯
Gerrit-Jan Weverling,

Affiliation Janssen Prevention Center, Leiden, The Netherlands
⨯
Frank de Wolf,

Affiliations Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom, Janssen Prevention Center, Leiden, The Netherlands
⨯
Roy M. Anderson

Affiliation Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom
⨯

Using Clinical Trial Simulators to Analyse the Sources of Variance in Clinical Trials of Novel Therapies for Acute Viral Infections

Carolin Vegvari,
Emilie Cauët,
Christoforos Hadjichrysanthou,
Emma Lawrence,
Gerrit-Jan Weverling,
Frank de Wolf,
Roy M. Anderson

Published: June 22, 2016
https://doi.org/10.1371/journal.pone.0156622

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