Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

Charis Pericleous; Isabel Ferreira; Orietta Borghi; Francesca Pregnolato; Thomas McDonnell; Acely Garza-Garcia; Paul Driscoll; Silvia Pierangeli; David Isenberg; Yiannis Ioannou; Ian Giles; Pier Luigi Meroni; Anisur Rahman

doi:10.1371/journal.pone.0156407

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Open Access

Peer-reviewed

Research Article

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

Charis Pericleous ,

* E-mail: c.pericleous@ucl.ac.uk

Affiliation Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom
⨯
Isabel Ferreira,

Affiliation Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom
⨯
Orietta Borghi,

Affiliation Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy
⨯
Francesca Pregnolato,

Affiliation Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy
⨯
Thomas McDonnell,

Affiliation Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom
⨯
Acely Garza-Garcia,

Affiliation Structural Biology, MRC National Institute for Medical Research, London, United Kingdom
⨯
Paul Driscoll,

Affiliation Structural Biology, MRC National Institute for Medical Research, London, United Kingdom
⨯
Silvia Pierangeli,

Affiliation Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
David Isenberg,

Affiliation Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom
⨯
Yiannis Ioannou,

Affiliations Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, Arthritis Research UK Centre for Adolescent Rheumatology, UCL Hospital and Great Ormond Street Hospital, London, United Kingdom
⨯
Ian Giles,

Affiliation Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom
⨯
Pier Luigi Meroni,

Affiliation Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy
⨯
Anisur Rahman

Affiliation Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom
⨯

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

Charis Pericleous,
Isabel Ferreira,
Orietta Borghi,
Francesca Pregnolato,
Thomas McDonnell,
Acely Garza-Garcia,
Paul Driscoll,
Silvia Pierangeli,
David Isenberg,
Yiannis Ioannou

Published: June 2, 2016
https://doi.org/10.1371/journal.pone.0156407

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