The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors

Jasbir D. Upadhyaya; Raja Chakraborty; Feroz A. Shaik; Appalaraju Jaggupilli; Rajinder P. Bhullar; Prashen Chelikani

doi:10.1371/journal.pone.0156347

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Open Access

Peer-reviewed

Research Article

The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors

Jasbir D. Upadhyaya,

Affiliations Department of Oral Biology, and Manitoba Chemosensory Biology (MCSB) Research group, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB, R3E 3P4, Canada
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Raja Chakraborty,

Affiliations Department of Oral Biology, and Manitoba Chemosensory Biology (MCSB) Research group, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB, R3E 3P4, Canada
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Feroz A. Shaik,

Affiliations Department of Oral Biology, and Manitoba Chemosensory Biology (MCSB) Research group, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB, R3E 3P4, Canada
⨯
Appalaraju Jaggupilli,

Affiliations Department of Oral Biology, and Manitoba Chemosensory Biology (MCSB) Research group, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB, R3E 3P4, Canada
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Rajinder P. Bhullar,

Affiliation Department of Oral Biology, and Manitoba Chemosensory Biology (MCSB) Research group, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada
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Prashen Chelikani

* E-mail: Prashen.Chelikani@umanitoba.ca

Affiliations Department of Oral Biology, and Manitoba Chemosensory Biology (MCSB) Research group, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB, R3E 3P4, Canada
⨯

The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors

Jasbir D. Upadhyaya,
Raja Chakraborty,
Feroz A. Shaik,
Appalaraju Jaggupilli,
Rajinder P. Bhullar,
Prashen Chelikani

Published: May 25, 2016
https://doi.org/10.1371/journal.pone.0156347

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