A Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the Complex

Open Access

Peer-reviewed

Research Article

Shailesh Tripathi,

Affiliation Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, 560029, India
⨯
Shruti Mathur,

Affiliation Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, 560029, India
⨯
Prashant Deshmukh,

Affiliation Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, 560029, India
⨯
Ramu Manjula,

Affiliation Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, 560029, India
⨯
Balasundaram Padmanabhan

* E-mail: paddy@nimhans.ac.in; balapaddy@gmail.com

Affiliation Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore, 560029, India
⨯

Reader Comments (0)

Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Hydrogen bonding
Is the Subject Area "Hydrogen bonding" applicable to this article?

Thanks for your feedback.
Molecular structure
Is the Subject Area "Molecular structure" applicable to this article?

Thanks for your feedback.
Electron density
Is the Subject Area "Electron density" applicable to this article?

Thanks for your feedback.
Binding analysis
Is the Subject Area "Binding analysis" applicable to this article?

Thanks for your feedback.
Histones
Is the Subject Area "Histones" applicable to this article?

Thanks for your feedback.
Chromatin
Is the Subject Area "Chromatin" applicable to this article?

Thanks for your feedback.
X-ray crystallography
Is the Subject Area "X-ray crystallography" applicable to this article?

Thanks for your feedback.