A Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST

Open Access

Peer-reviewed

Research Article

Panuwat Trairatphisan,

Affiliation Systems Biology group, Life Sciences Research Unit, University of Luxembourg, Luxembourg, Luxembourg

http://orcid.org/0000-0002-1124-5375

⨯
Monique Wiesinger,

Affiliation Systems Biology group, Life Sciences Research Unit, University of Luxembourg, Luxembourg, Luxembourg
⨯
Christelle Bahlawane,

Affiliation Molecular disease mechanisms group, Life Sciences Research Unit, University of Luxembourg, Luxembourg, Luxembourg
⨯
Serge Haan,

Affiliation Molecular disease mechanisms group, Life Sciences Research Unit, University of Luxembourg, Luxembourg, Luxembourg
⨯
Thomas Sauter

* E-mail: thomas.sauter@uni.lu

Affiliation Systems Biology group, Life Sciences Research Unit, University of Luxembourg, Luxembourg, Luxembourg
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Cellular crosstalk
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Signaling networks
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MAPK signaling cascades
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Signal inhibition
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STAT signaling
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Optimization
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Oncogenic signaling
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Point mutation
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