Leukocyte-Rich Platelet-Rich Plasma Injections Do Not Up-Modulate Intra-Articular Pro-Inflammatory Cytokines in the Osteoarthritic Knee

Open Access

Peer-reviewed

Research Article

Erminia Mariani,

Affiliations Laboratory of Immunorheumatology and Tissue Regeneration/RAMSES, Rizzoli Orthopaedic Institute, Bologna, Italy, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
⨯
Valentina Canella,

Affiliation Laboratory of Immunorheumatology and Tissue Regeneration/RAMSES, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯
Luca Cattini,

Affiliation Laboratory of Immunorheumatology and Tissue Regeneration/RAMSES, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯
Elizaveta Kon,

Affiliation Laboratory of Biomechanics and Technology Innovation/NABI, 2nd Orthopaedic and Traumatologic Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯
Maurilio Marcacci,

Affiliation Laboratory of Biomechanics and Technology Innovation/NABI, 2nd Orthopaedic and Traumatologic Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯
Berardo Di Matteo ,

* E-mail: bdimatteo@biomec.ior.it

Affiliation Laboratory of Biomechanics and Technology Innovation/NABI, 2nd Orthopaedic and Traumatologic Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯
Lia Pulsatelli,

Affiliation Laboratory of Immunorheumatology and Tissue Regeneration/RAMSES, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯
Giuseppe Filardo

Affiliation Laboratory of Biomechanics and Technology Innovation/NABI, 2nd Orthopaedic and Traumatologic Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy
⨯

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Synovial fluid
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Cytokines
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White blood cells
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Cytokine therapy
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Platelets
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Inflammation
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Blood plasma
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Growth factors
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