Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis

• Xiaoping Lin ,

  Contributed equally to this work with: Xiaoping Lin, Ryuya Fukunaga

  Affiliations Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America, Department of Cardiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China

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• Steven Steinberg,

  Affiliation Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Suresh K. Kandasamy,

  Affiliation Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD, United States of America

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• Junaid Afzal,

  Affiliation Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Blaid Mbiyangandu,

  Affiliation Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Susan E. Liao,

  Affiliation Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD, United States of America

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• Yufan Guan,

  Affiliation Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Celia P. Corona-Villalobos,

  Affiliation Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Scot J. Matkovich,

  Affiliation Center for Pharmacogenomics, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, United States of America

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• Neal Epstein,

  Affiliation Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States of America

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• Dotti Tripodi,

  Affiliation Laboratory of Molecular Cardiology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States of America

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• Zhaoxia Huo,

  Affiliation Clinical Research Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China

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• Garry Cutting,

  Affiliation Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Theodore P. Abraham,

  Affiliation Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Ryuya Fukunaga ,

  Contributed equally to this work with: Xiaoping Lin, Ryuya Fukunaga

  * E-mail: mabraha3@jhmi.edu (MRA); fukunaga@jhmi.edu (RF)

  Affiliation Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD, United States of America

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•  [ ... ],
• M. Roselle Abraham

  * E-mail: mabraha3@jhmi.edu (MRA); fukunaga@jhmi.edu (RF)

  Affiliation Hypertrophic Cardiomyopathy Center of Excellence, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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