Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations

• Bajarang Vasant Kumbhar ,

  Contributed equally to this work with: Bajarang Vasant Kumbhar, Anubhaw Borogaon

  Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai-400076, Maharashtra, India

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• Anubhaw Borogaon ,

  Contributed equally to this work with: Bajarang Vasant Kumbhar, Anubhaw Borogaon

  Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai-400076, Maharashtra, India

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• Dulal Panda ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai-400076, Maharashtra, India

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• Ambarish Kunwar

  * E-mail: akunwar@iitb.ac.in

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai-400076, Maharashtra, India

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