Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma

• Victor Hugo Villar,

  Current address: Institut Européen de Chimie et Biologie, Pessac, INSERM U916 VINCO, Institut Bergonié, Bordeaux, France

  Affiliation Group of Clinical and Translational Research, Department of Biology, Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS), University of the Balearic Islands, Palma de Mallorca, Spain

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• Oliver Vögler,

  Affiliation Group of Clinical and Translational Research, Department of Biology, Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS), University of the Balearic Islands, Palma de Mallorca, Spain

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• Francisca Barceló,

  Affiliation Group of Clinical and Translational Research, Department of Biology, Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS), University of the Balearic Islands, Palma de Mallorca, Spain

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• Javier Martín-Broto,

  Affiliations Group of Clinical and Translational Research, Department of Biology, Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS), University of the Balearic Islands, Palma de Mallorca, Spain, Department of Oncology, University Hospital Virgen del Rocío and Biomedicine Institute of Sevilla (IBIS), Sevilla, Spain

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• Jordi Martínez-Serra,

  Affiliations Group of Clinical and Translational Research, Department of Biology, Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS), University of the Balearic Islands, Palma de Mallorca, Spain, Department of Hematology, University Hospital Son Espases, Palma de Mallorca, Spain

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• Valentina Ruiz-Gutiérrez,

  Affiliations Instituto de la Grasa, Consejo Superior de Investigaciones Científicas (CSIC), Sevilla, Spain, CIBER:CB06/03 Fisiopatología de la Obesidad y la Nutrición, CIBERobn, Instituto de Salud, Carlos III (ISCIII), Spain

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• Regina Alemany

  * E-mail: regina.alemany@uib.es

  Affiliations Group of Clinical and Translational Research, Department of Biology, Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS), University of the Balearic Islands, Palma de Mallorca, Spain, CIBER:CB06/03 Fisiopatología de la Obesidad y la Nutrición, CIBERobn, Instituto de Salud, Carlos III (ISCIII), Spain

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