G-Protein/β-Arrestin-Linked Fluctuating Network of G-Protein-Coupled Receptors for Predicting Drug Efficacy and Bias Using Short-Term Molecular Dynamics Simulation

• Osamu Ichikawa,

  Affiliation Genomic Science Laboratories, Sumitomo Dainippon Pharma. Co. Ltd, Osaka, Osaka, Japan

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• Kazushi Fujimoto,

  Affiliation Department of Applied Chemistry, Nagoya University, Nagoya, Aichi, Japan

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• Atsushi Yamada,

  Affiliation Department of Applied Chemistry, Nagoya University, Nagoya, Aichi, Japan

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• Susumu Okazaki,

  Affiliation Department of Applied Chemistry, Nagoya University, Nagoya, Aichi, Japan

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• Kazuto Yamazaki

  * E-mail: kazuto-yamazaki@ds-pharma.co.jp

  Affiliation Genomic Science Laboratories, Sumitomo Dainippon Pharma. Co. Ltd, Osaka, Osaka, Japan

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