Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia

Emilio Fernandez-Egea; Petra E. Vértes; Shaun M. Flint; Lorinda Turner; Syed Mustafa; Alex Hatton; Kenneth G. C. Smith; Paul A. Lyons; Edward T. Bullmore

doi:10.1371/journal.pone.0155631

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Peer-reviewed

Research Article

Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia

Emilio Fernandez-Egea ,

Contributed equally to this work with: Emilio Fernandez-Egea, Petra E. Vértes, Shaun M. Flint

Affiliations NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge, Cambridge, United Kingdom, University of Cambridge, Behavioural & Clinical Neuroscience Institute, Department of Psychiatry, Cambridge, United Kingdom, Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), G04, Barcelona, Spain, Cambridgeshire & Peterborough NHS Foundation Trust, Cambridge, United Kingdom

http://orcid.org/0000-0003-4128-8955

⨯
Petra E. Vértes ,

Contributed equally to this work with: Emilio Fernandez-Egea, Petra E. Vértes, Shaun M. Flint

Affiliation University of Cambridge, Behavioural & Clinical Neuroscience Institute, Department of Psychiatry, Cambridge, United Kingdom
⨯
Shaun M. Flint ,

Contributed equally to this work with: Emilio Fernandez-Egea, Petra E. Vértes, Shaun M. Flint

Affiliation Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, School of Clinical Medicine, Cambridge, United Kingdom
⨯
Lorinda Turner,

Affiliations NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge, Cambridge, United Kingdom, Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, School of Clinical Medicine, Cambridge, United Kingdom
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Syed Mustafa,

Affiliation University of Cambridge, Behavioural & Clinical Neuroscience Institute, Department of Psychiatry, Cambridge, United Kingdom
⨯
Alex Hatton,

Affiliation Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, School of Clinical Medicine, Cambridge, United Kingdom
⨯
Kenneth G. C. Smith,

Affiliations NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge, Cambridge, United Kingdom, Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, School of Clinical Medicine, Cambridge, United Kingdom
⨯
Paul A. Lyons,

Affiliation Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, School of Clinical Medicine, Cambridge, United Kingdom
⨯
Edward T. Bullmore

* E-mail: etb23@cam.ac.uk

Affiliations NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge, Cambridge, United Kingdom, University of Cambridge, Behavioural & Clinical Neuroscience Institute, Department of Psychiatry, Cambridge, United Kingdom, Cambridgeshire & Peterborough NHS Foundation Trust, Cambridge, United Kingdom, GlaxoSmithKline, ImmunoPsychiatry, Alternative Discovery & Development, Pharmaceutical R&D, Cambridge, United Kingdom
⨯

Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia

Emilio Fernandez-Egea,
Petra E. Vértes,
Shaun M. Flint,
Lorinda Turner,
Syed Mustafa,
Alex Hatton,
Kenneth G. C. Smith,
Paul A. Lyons,
Edward T. Bullmore

Published: May 31, 2016
https://doi.org/10.1371/journal.pone.0155631

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