Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway

Deqiang Han; Junbo Liang; Yalan Lu; Longchang Xu; Shiying Miao; Lin-Yu Lu; Wei Song; Linfang Wang

doi:10.1371/journal.pone.0155476

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Open Access

Peer-reviewed

Research Article

Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway

Deqiang Han,

Affiliations Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, Department of Cancer Genetics and Epigenetics; Beckman Research Institute; City of Hope, Duarte, California, United States of America
⨯
Junbo Liang,

Affiliation Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
⨯
Yalan Lu,

Affiliation Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
⨯
Longchang Xu,

Affiliation Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
⨯
Shiying Miao,

Affiliation Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
⨯
Lin-Yu Lu,

Affiliations Key Laboratory of Reproductive Genetics, Ministry of Education and Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China, Institute of Translational Medicine, Zhejiang University, Hangzhou, Zhejiang, China
⨯
Wei Song ,

* E-mail: songwei@ibms.pumc.edu.cn (WS); lfwangz@yahoo.com (LW)

Affiliation Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
⨯
Linfang Wang

* E-mail: songwei@ibms.pumc.edu.cn (WS); lfwangz@yahoo.com (LW)

Affiliation Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
⨯

Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway

Deqiang Han,
Junbo Liang,
Yalan Lu,
Longchang Xu,
Shiying Miao,
Lin-Yu Lu,
Wei Song,
Linfang Wang

Published: May 19, 2016
https://doi.org/10.1371/journal.pone.0155476

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