Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8⁺ T Cells

• Lin Sun ,

  Contributed equally to this work with: Lin Sun, Anthony J. St. Leger

  Affiliation Molecular Immunology Section, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America

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• Anthony J. St. Leger ,

  Contributed equally to this work with: Lin Sun, Anthony J. St. Leger

  Affiliation Immunoregulation Section, NEI, NIH, Bethesda, Maryland, United States of America

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• Cheng-Rong Yu,

  Affiliation Molecular Immunology Section, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America

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• Chang He,

  Current address: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, P. R. China

  Affiliation Molecular Immunology Section, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America

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• Rashid M. Mahdi,

  Affiliation Molecular Immunology Section, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America

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• Chi-Chao Chan,

  Affiliation Immunopathology Section, NEI, NIH, Bethesda, Maryland, United States of America

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• Hongsheng Wang,

  Affiliation Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Rockville, Maryland, United States of America

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• Herbert C. Morse III,

  Affiliation Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Rockville, Maryland, United States of America

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• Charles E. Egwuagu

  * E-mail: egwuaguc@nei.nih.gov

  Affiliation Molecular Immunology Section, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America

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