Combined Exposure to Simulated Microgravity and Acute or Chronic Radiation Reduces Neuronal Network Integrity and Survival

Giuseppe Pani; Mieke Verslegers; Roel Quintens; Nada Samari; Louis de Saint-Georges; Patrick van Oostveldt; Sarah Baatout; Mohammed Abderrafi Benotmane

doi:10.1371/journal.pone.0155260

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Open Access

Peer-reviewed

Research Article

Combined Exposure to Simulated Microgravity and Acute or Chronic Radiation Reduces Neuronal Network Integrity and Survival

Giuseppe Pani ,

Contributed equally to this work with: Giuseppe Pani, Mieke Verslegers

Affiliations Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium, Cell Systems and Imaging Research Group (CSI), Department of Molecular Biotechnology, Ghent University, Ghent, Belgium, Laboratory of Membrane Biochemistry and Applied Nutrition, Department of Pharmacology and Bio-molecular Sciences (DiSFeB), Università degli Studi di Milano, Milano, Italy
⨯
Mieke Verslegers ,

Contributed equally to this work with: Giuseppe Pani, Mieke Verslegers

Affiliation Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium
⨯
Roel Quintens,

Affiliation Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium
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Nada Samari,

Affiliation Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium
⨯
Louis de Saint-Georges,

Affiliation Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium
⨯
Patrick van Oostveldt,

Affiliation Cell Systems and Imaging Research Group (CSI), Department of Molecular Biotechnology, Ghent University, Ghent, Belgium
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Sarah Baatout,

Affiliations Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium, Cell Systems and Imaging Research Group (CSI), Department of Molecular Biotechnology, Ghent University, Ghent, Belgium
⨯
Mohammed Abderrafi Benotmane

* E-mail: abenotma@sckcen.be

Affiliation Radiobiology Unit, Laboratory of Molecular and Cellular Biology, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre, SCK•CEN, Mol, Belgium
⨯

Combined Exposure to Simulated Microgravity and Acute or Chronic Radiation Reduces Neuronal Network Integrity and Survival

Giuseppe Pani,
Mieke Verslegers,
Roel Quintens,
Nada Samari,
Louis de Saint-Georges,
Patrick van Oostveldt,
Sarah Baatout,
Mohammed Abderrafi Benotmane

Published: May 20, 2016
https://doi.org/10.1371/journal.pone.0155260

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