Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

Marco Fiocchetti; Manuela Cipolletti; Stefano Leone; Antonella Naldini; Fabio Carraro; Daniela Giordano; Cinzia Verde; Paolo Ascenzi; Maria Marino

doi:10.1371/journal.pone.0154959

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Open Access

Peer-reviewed

Research Article

Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

Marco Fiocchetti,

Affiliation Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, I-00146 Roma, Italy
⨯
Manuela Cipolletti,

Affiliation Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, I-00146 Roma, Italy
⨯
Stefano Leone,

Affiliation Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, I-00146 Roma, Italy
⨯
Antonella Naldini,

Affiliation Department of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
⨯
Fabio Carraro,

Affiliation Department of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
⨯
Daniela Giordano,

Affiliation Biosciences and BioResources Institute—CNR, Via Pietro Castellino 111, 80131 Napoli, Italy
⨯
Cinzia Verde,

Affiliations Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, I-00146 Roma, Italy, Biosciences and BioResources Institute—CNR, Via Pietro Castellino 111, 80131 Napoli, Italy
⨯
Paolo Ascenzi,

Affiliations Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, I-00146 Roma, Italy, Biosciences and BioResources Institute—CNR, Via Pietro Castellino 111, 80131 Napoli, Italy, Interdepartmental Laboratory of Electron Microscopy, Roma Tre University, Via della Vasca Navale 79, I-00146 Roma, Italy
⨯
Maria Marino

* E-mail: maria.marino@uniroma3.it

Affiliations Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, I-00146 Roma, Italy, Biosciences and BioResources Institute—CNR, Via Pietro Castellino 111, 80131 Napoli, Italy
⨯

Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

Marco Fiocchetti,
Manuela Cipolletti,
Stefano Leone,
Antonella Naldini,
Fabio Carraro,
Daniela Giordano,
Cinzia Verde,
Paolo Ascenzi,
Maria Marino

Published: May 5, 2016
https://doi.org/10.1371/journal.pone.0154959

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Breast cancer
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