Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

Chongwei Chen; Xiaochun Wei; Zhi Lv; Xiaojuan Sun; Shaowei Wang; Yang Zhang; Qiang Jiao; Xiaohu Wang; Yongping Li; Lei Wei

doi:10.1371/journal.pone.0154951

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Peer-reviewed

Research Article

Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

Chongwei Chen,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Xiaochun Wei,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Zhi Lv,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Xiaojuan Sun,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Shaowei Wang,

Affiliations Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China, Department of Orthopaedics, Warren Alpert Medical School of Brown University/Rhode Island Hosptal, Providence, Rhode Island, United States of America
⨯
Yang Zhang,

Affiliations Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China, Department of Orthopaedics, Warren Alpert Medical School of Brown University/Rhode Island Hosptal, Providence, Rhode Island, United States of America
⨯
Qiang Jiao,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Xiaohu Wang,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Yongping Li,

Affiliation Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China
⨯
Lei Wei

* E-mail: lei_wei@brown.edu

Affiliations Department of Orthopaedics, the Second Hospital of Shanxi Medical University; Shanxi Key Lab of Bone and Soft Tissue Injury Repair, Taiyuan, Shanxi, China, Department of Orthopaedics, Warren Alpert Medical School of Brown University/Rhode Island Hosptal, Providence, Rhode Island, United States of America
⨯

Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

Chongwei Chen,
Xiaochun Wei,
Zhi Lv,
Xiaojuan Sun,
Shaowei Wang,
Yang Zhang,
Qiang Jiao,
Xiaohu Wang,
Yongping Li,
Lei Wei

Published: May 5, 2016
https://doi.org/10.1371/journal.pone.0154951

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Gene expression
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Transfection
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