Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors

Natalia González; James J. Moresco; Felipe Cabezas; Eduardo de la Vega; Francisco Bustos; John R. Yates III; Hugo C. Olguín

doi:10.1371/journal.pone.0154919

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Peer-reviewed

Research Article

Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors

Natalia González,

Affiliation Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile
⨯
James J. Moresco,

Affiliation Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, United States of America
⨯
Felipe Cabezas ,

Contributed equally to this work with: Felipe Cabezas, Eduardo de la Vega

Affiliation Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile
⨯
Eduardo de la Vega ,

Contributed equally to this work with: Felipe Cabezas, Eduardo de la Vega

Affiliation Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile
⨯
Francisco Bustos,

Current address: Medical Research Council Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee, Sir James Black Centre School of Life Sciences, Dundee, DD1 5EH, United Kingdom

Affiliation Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile
⨯
John R. Yates III,

Affiliation Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, United States of America
⨯
Hugo C. Olguín

* E-mail: holguin@bio.puc.cl

Affiliation Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile
⨯

Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors

Natalia González,
James J. Moresco,
Felipe Cabezas,
Eduardo de la Vega,
Francisco Bustos,
John R. Yates III,
Hugo C. Olguín

Published: May 4, 2016
https://doi.org/10.1371/journal.pone.0154919

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Phosphorylation
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Muscle differentiation
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Myoblasts
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Transfection
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Ubiquitination
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Muscle proteins
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Cell differentiation
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Skeletal muscles
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